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Fathers’ microplastic exposure may raise diabetes risk in kids: Study

Shows female offspring of male mice exposed to microplastics are more susceptible to metabolic disorders

Fathers’ microplastic exposure may raise diabetes risk in kids: Study

Fathers’ microplastic exposure may raise diabetes risk in kids: Study
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29 Dec 2025 8:53 AM IST

A father’s exposure to microplastics can trigger metabolic dysfunctions in children, with daugh-ters more at risk of developing diabetes, according to animal studies.

Microplastics are tiny plastic particles (less than 5 millimetres) resulting from the breakdown of consumer products and industrial waste. While microplastics have already been detected in human reproductive systems, the study, pub-lished in the Journal of the Endocrine Society, is the first to bridge the gap between paternal ex-posure to microplastics and the long-term health of the next generation.

“Our discovery opens a new frontier in environmental health, shifting the focus toward how both parents’ environments contribute to the health of their children,” said lead author Changcheng Zhou, Professor of biomedical sciences in the University of California, Riverside’s School of Medicine.

“These findings from a mouse study likely have implications for humans. Men planning to have children should consider reducing their exposure to harmful substances like microplastics to pro-tect both their health and that of their future children,” Zhou added.

For the study, the team induced metabolic disorders -- such as increased blood pressure, high blood sugar, and excess body fat -- in mouse models by feeding them a high-fat diet.

The findings showed that female offspring of male mice exposed to microplastics were signifi-cantly more susceptible to metabolic disorders than offspring of unexposed fathers, despite all offspring being fed the same high-fat diet.

“The exact reasons for this sex-specific effect are still unclear,” Zhou said.

Microplastics health risks Paternal environmental exposure Metabolic disorders diabetes risk Environmental toxins reproductive health Emerging research environmental health 
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