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2,501 new mpox cases, 12 deaths reported from 44 countries in Oct: WHO

When mpox outbreaks are not rapidly contained, and human-to-human transmission is not interrupted, there is a risk of sustained community transmission

2,501 new mpox cases, 12 deaths reported from 44 countries in Oct: WHO

2,501 new mpox cases, 12 deaths reported from 44 countries in Oct: WHO
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10 Dec 2025 10:22 AM IST

A total of 2,501 new confirmed cases, including 12 deaths due to mpox, were reported from 44 countries in October, said the World Health Organization (WHO) on Tuesday.

The latest situation report for the multi-country outbreak of mpox showed that all clades of the monkeypox virus (MPXV) continue to circulate.

When mpox outbreaks are not rapidly contained, and human-to-human transmission is not interrupted, there is a risk of sustained community transmission.

“In October 2025, 44 countries, across all WHO regions, reported a total of 2,501 new confirmed mpox cases, including 12 deaths (case fatality ratio [CFR] 0.5 per cent),” the WHO report said.

Twenty-one countries in Africa reported active transmission of mpox in the last six weeks (from October 12 to November 23), with 1,734 confirmed cases, including 10 deaths.

Mpox Outbreak 2025 WHO Situation Report Global Health Surveillance Monkeypox Transmission Risk Public Health Alert 
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