Metabolic Health Even Without Weight Loss

Jerusalem: People can improve their health through dietary and lifestyle changes even if they do not lose weight, according to an international study.

The research, conducted by the universities of Ben-Gurion (Israel), Harvard (US), and Leipzig (Germany), focused on individuals described as "weight loss resistant".

“We have been conditioned to equate weight loss with health, and weight loss-resistant individuals are often labeled as failures,” said lead author Anat Yaskolka Meir, postdoctoral research fellow in the Department of Epidemiology at Harvard Chan School. “Our findings reframe how we define clinical success. People who do not lose weight can improve their metabolism and reduce their long-term risk for disease. That’s a message of hope, not failure,” Meir added.

Published in the European Journal of Preventive Cardiology, the study challenges the long-standing belief that weight loss is the primary sign of a successful diet. Researchers found that even participants who did not lose weight showed measurable improvements in key health indicators. Researchers identified 12 genetic markers that may influence whether a person is likely to lose weight through lifestyle changes, an insight that could help personalise future diet plans.